Jazz Pharmaceuticals is undertaking a bold, enterprise-wide transformation to reimagine our operating model and build a patient-centric, agile, and scalable rare disease organization delivering differentiated, precise customer experiences.

The Executive Director, Enterprise Transformation- Tech Ops and G&A is a senior, enterprise leader responsible for setting direction and driving execution of one or more mission-critical transformation programs that shape the future of Jazz. This role operates as a trusted advisor and strategic partner to the Executive Committee (EC), with accountability for designing, orchestrating, and embedding large-scale change across functions.

This is a high-visibility, high-impact executive role for a leader who operates comfortably at the most senior levels of the organization, influences without authority, and balances strategic vision with hands-on execution. The Executive Director will lead complex, multi-year initiatives, navigate ambiguity, and challenge the status quo to deliver measurable, sustainable outcomes.

Key Responsibilities 

Enterprise Transformation Strategy & Vision

• Translate Jazz’s enterprise transformation vision into integrated, multi-year strategies, roadmaps, and value cases across assigned functional or enterprise domains.

• Partner with the Chief Transformation Officer and EC members to identify, prioritize, and shape transformation initiatives that drive a high performing organization, growth, patient impact and cost efficiency.

• Define future-state operating models considering portfolio evolution, market dynamics, digital enablement, and organizational capabilities.

End-to-End Transformation Leadership

• Serve as accountable executive owner for major transformation programs, with responsibility for outcomes from concept through full-scale implementation and sustainment.

• Lead complex initiatives spanning multiple workstreams, functions, and geographies, ensuring alignment to enterprise objectives and interdependencies.

• Oversee design and implementation of new ways of working, including structure, governance, decision rights, processes, incentives, capabilities, and technology.

Executive Partnership & Influence

• Act as a thought partner and challenger to senior leaders, providing objective insight, rigorous analytics, and scenario-based recommendations.

• Engage in productive challenge with EC members and functional leaders to drive alignment, resolve trade-offs, and accelerate decision-making.

• Represent transformation progress, risks, and outcomes to the Executive Committee and other senior governance forums.

Change Leadership & Organizational Adoption

• Set the change agenda and ensure deep, lasting embedding of transformation outcomes across Jazz.

• Lead enterprise-wide change management strategies, including stakeholder engagement, communications, capability building, and cultural reinforcement.

• Anticipate and actively manage resistance, enabling leaders and teams to adopt new mindsets and behaviors aligned with a customer- and patient-first orientation.

Cross-Functional & Matrix Leadership

• Lead and develop matrixed transformation teams and workstream leaders, fostering accountability, collaboration, and high performance.

• Partner closely with executive leaders of assigned functions (e.g., R&D, Commercial, G&A, Digital) to ensure seamless integration and execution of transformation initiatives.

• Model enterprise thinking and drive solutions that optimize outcomes for Jazz as a whole, not individual functions.

Performance Management & Value Delivery

• Define enterprise-level KPIs, success metrics, and value realization plans linked to transformation objectives.

• Monitor progress rigorously, course-correct as needed, and ensure delivery of committed outcomes.

• Provide transparent, executive-level reporting on milestones, risks, and impact.

Qualifications 

• Bachelor’s degree required; advanced degree (MBA, PhD, or equivalent) preferred.

• 12+ years of progressive leadership experience in life sciences, healthcare, management consulting, or enterprise transformation roles.

• Proven record of leading large-scale, complex, cross-functional transformations with measurable business impact.

• Demonstrated ability to operate credibly at the Executive Committee level, including preparing and delivering executive-level presentations.

• Deep expertise in one or more areas such as Commercial, R&D, G&A, digital transformation, operating model design, or enterprise change.

• Strong systems thinker with the ability to connect strategy, data, operating models, and culture.

• Highly effective influencer who works across silos and leads through ambiguity without direct authority.

• Exceptional analytical, strategic, and problem-solving capabilities.

• Experience with agile, design thinking, lean, or modern change methodologies strongly preferred.

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